Everything you eat and drink, including nutritional supplements, must be made isotonic before passing into your small intestine where it can be absorbed.
In the time that it takes for most pills and capsules to disintegrate, and their contents to dissolve and transform to the proper isotonic state, much of their activity is lost. During digestion, the important micronutrients in pills and capsules can get trapped by fats, fibers, and tannins or inactivated by the highly acidic pH level of your stomach.
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